Multi-Level Kinetic Model of mRNA Delivery via Transfection of Lipoplexes
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چکیده
منابع مشابه
Multi-Level Kinetic Model of mRNA Delivery via Transfection of Lipoplexes
Recent work on the use of mRNA lipoplexes for gene delivery demonstrates the need for a mathematical model that simulates and predicts kinetics and transfection efficiency. The small copy numbers involved make it necessary to use stochastic models and include statistical analysis of the variation observed in the experimental data. The modeling requirements are further complicated by the multi-l...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2014
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0107148